What 80 Biologists Working on the First Synthetic Yeast Chromosome Wish they had

With the most recent triumph of developing the world’s first completely synthetic eukaryotic chromosome under the leadership of Dr. Jef Boeke’s Johns Hopkins lab it is clear that ambitions within the field of Synthetic Biology are growing larger every day. With these incredible undertakings come larger sequences, and with these larger sequences come larger teams…

First Eukaryotic chromosome Synthesized

Instead of just copying nature, the team did extensive tinkering with their chromosome, deleting unwanted genes here and there. It then successfully incorporated the designer chromosome into living yeast cells, endowing them with new capabilities not found in naturally occurring yeast. The most familiar yeast is commonly referred to as brewers’ yeast, saccharomyces cerevisiae, which is a…